Compared to livers from control mice, those from HFD-fed mice showed a significantly increased percentage of methylation at the CpG islands of CYP2R1 (Fig
Additionally, when this version of reduced-BSA homemade B-27 was used, the differentiation medium was supplemented with Insulin-Transferrin-Selenium (ITS) supplement (Gibco, catalog no
GSH levels in macrophages, directly affect the Th1/Th2 cytokine response, and more specifically, GSH depletion inhibits Th1-associated cytokine production and/or promotes Th2 associated responses (Fraternale et al., 2006)
The RAW files were uploaded to Integrated Proteomics Pipeline (IP2) and searched using the ProLuCID algorithm (publicly available at using a reverse concatenated, non-redundant version of the Mouse UniProt database (release 2017)
Loscalzo,Redox regulation of mitochondrial function.Antioxid Redox Signal, 2012