[DOI] [PubMed] [Google Scholar] 51.Piccoli GF, Mesquita LA, Stein C, Aziz M, Zoldan M, Degobi NAH, et al
And subscribe to the Med Info Monthly newsletter FDA (OPDP) recently issued a second untitled letter in a 2 week period
Compounding pharmacies have been able to step in and fill some of those gaps in the marketplace. Most states have similar compounding rules, though some states including California and Texas are stricter than others
Because of an increased risk of diabetic ketoacidosis ketone monitoring in patients with type 1 diabetes and in others at risk for ketoacidosis (patients with type 2 diabetes on insulin therapy) should be considered, particularly when precipitating conditions for diabetic ketoacidosis occur such as acute febrile illness, reduced caloric intake, ketogenic diet, surgery, insulin dose reduction, volume depletion, or alcohol abuse
Tirzepatide, which activates both GLP-1 and GIP receptors, engages a broader signaling cascade and may produce more pronounced gastrointestinal effects in genetically sensitive individuals