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Consequently, frataxin deficiency leads to impaired activity of Fe-S cluster-containing enzymes, resulting in reduced OXPHOS efficiency, decreased ATP production, and compromised aconitase activity (Fig

In addition, As 2 O 3 also plays an important role in the treatment of acute promyelocytic leukemia, promoting cell apoptosis by inducing ROS accumulation [472, 473]

Published August 29, 2024

It was found that six RNA modification-related genes (ADAMDEC1, IGHM, OGN, TNFRSF11B, SCARA3 and PTN) were identified as possible biomarkers of OA and RA pathogenesis [124]

Data availability Uncropped western blot images are provided in Supplementary Fig