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Two different conditions were employed: endpoint A, where the medium was supplemented with an excipient (citrate-phosphate buffer, pH 5, Merck, Darmstadt, Germany), and endpoint B, where the medium was supplemented with cyanocobalamin (Merck) at a final concentration of 1 nM
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After 4 weeks at the 0.25 mg dosage, the dosage should be increased to 0.5 mg once weekly
As a researcher I require the highest standards
Up to 8 doses per month may be recommended
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