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Research demonstrates GHK-Cu modulates over 4,000 human genes, stimulates collagen I, III, and elastin synthesis, activates matrix metalloproteinases for extracellular matrix remodelling, promotes wound contraction and angiogenesis, and suppresses pro-inflammatory TNF- signalling

The treatment regimen consisted of a 6-day dose escalation (0.6, 1.2, 2.4, 4.8, 12, and 30 nmol/kg/day) to a maintenance dose of 30 nmol/kg/day for 12 weeks

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Its legal status reflects the absence of completed clinical trials rather than a safety determination