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As reported on MedPage Today, large retrospective study suggests that glucagon-like peptide-1 (GLP-1) receptor agonists may offer broad health benefits for patients with hidradenitis suppurativa (HS), extending beyond their established roles in diabetes and obesity management

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These genes include 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 ( HMGCLL1 ), thrombospondin 1 ( THBS1 ), uncoupling protein 3 ( UCP3 ), enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase ( EHHADH ), and sorting nexin 4 ( SNX4 )

Tirzepatide's profile differs slightly because GIP receptor co-agonism may modulate gastric emptying differently, though nausea still occurred in up to 31% of participants in SURMOUNT-1 [1]

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