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Whether this should be regarded as specific metabolic treatment, targeting only the metabolic alterations of the syndrome, is debatable, since the improvement in metabolic conditions, e.g., insulin resistance, would tenably have a positive impact also in gonadal function in women with PCOS

The fragment appeared to act through a mechanism distinct from the growth hormone receptor, suggesting a favorable safety profile compared to full-length GH [2]

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After day 56, the semaglutide plasma concentration in subjects randomised to semaglutide 1.0 mg increased as these subjects started treatment with a 1.0 mg dose