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Environmental influences during embryonic development in vitro affect an individuals susceptibility to epigenetic alterations and diseases such as cardiovascular disease, raising concerns about the potential consequences of IVF on the long-term health of offspring

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Toxicology 149:4350 Thomas C, Mackey MM, Diaz AA, Cox DP (2009) Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation

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People with certain medical conditions, like asthma, kidney disease, or liver disease, should not take it