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Some mild tightening can occur, but significant laxity usually requires collagen-stimulating treatments

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25 RCOOH + R'OH RCOOR' + H 2 O [1] 26Par consquent, l'eau gnre au cours de l'estrification enzymatique doit tre limine afin de poursuivre la raction (Chamouleau et al., 2001)

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In asthma, the pathogenesis of excessive mucus production is primarily attributed to increased numbers of goblet cells, which are stimulated by inflammatory mediators such as leukotrienes, proteolytic enzymes, and neuropeptides [70, 71]