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When in doubt, evaluation in an emergency department is appropriate, as acute pancreatitis can rapidly progress to serious complications including pancreatic necrosis, systemic inflammatory response, and multi-organ failure

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Nevertheless, it is crucial to consider the potential adverse effects of weight fluctuation after discontinuing these medications, particularly the increased risk of cardiovascular and all-cause mortality in patients with obesity or overweight

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Retatrutide should not be treated as a stand-alone approach for alcohol cravings or alcohol use disorder