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While this may seem contradictory to ADHD hyperactivity, it has been described as a response to seeking new stimuli once attention fades [98]

Estrogen is proposed to exert its effects through activation of the MAP kinase pathway and transcription factor NF-B, leading to increased expression of antioxidant enzymes such as superoxide dismutase (Farhat et al., 2017

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Astrocytes mediate neuroinflammation by acting as key intermediaries between the CNS and immune system, expressing cytokine receptors for IL-1, IL-6, TNF-, and IFN-, enabling them to sense immune signals [95]