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Trace Elements Med

doi:10.1038/s41380-020-00981-3

Beyond the A 2A receptor, other microglial receptors have emerged as promising therapeutic targets

The most impressive structural feature of peptide 20 is the lipidated K10 P by a 16-carbon palmitic acid through a -carboxylate spacer, which perfectly inserted into the TM1-TM2 crevice and made extensive contacts with both receptors and lipid membrane to stabilize the binding poses (Fig

3 Results 3.1 Levels of total, reduced and oxidized glutathione in the heart tissue The analysis of total glutathione content showed no difference between the heart of old and adult rats (Figure 1A)