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doi:10.1016/j.neuropsychologia.2018.01.003 Mion F, Pellissier S, Garros A, Damon H, Roman S, Bonaz B

Biomedicine 12:894

While a temporary decrease in NCOA4 results in less breakdown of ferritin, leading to increased iron storage and therefore less available iron in the cell [41], long-term reduction in NCOA4 expression or function, as observed in animal studies, leads to an overload of iron and oxidative stress [42]