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In their article, the researchers detail how these medications can both directly and indirectly reduce liver fat, inflammation, and fibrosis, potentially improving disease outcomes

JAMA 325(14):14141425

HDL, high density lipoprotein

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Various GLP-1RAs have been demonstrated to have significant benefits in in vitro and in vivo models of neurodegenerative diseases through modulating a variety of pathogenic mechanisms, including neuroinflammation, autophagy, mitochondrial dysfunction, and the abnormal phosphorylation of pathognomonic proteins