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Relevant plasmids and sequences have been deposited in Addgene (www.addgene.org) with the following IDs: pETSG, 159418

This duality underscores the critical importance of microbial community composition over total amino acid load: a eubiotic microbiome channels tryptophan and methionine toward protective metabolites, whereas dysbiosis skews production toward nephrotoxins

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Further analysis of signaling pathways confirmed that PD effectively upregulated endogenous TGF-/Nodal signaling and downstream Smad2/3 transduction, while concurrently downregulating BMP signaling, leading to robust DE formation

The skin around your eyes is the thinnest on your entire face, which means it shows stress, fatigue, and age faster than anywhere else