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Therefore, it is important for the neuroscientist to carefully monitor the locomotor changes (decreased movements, balance, and muscle strength) associated with coordination difficulty ( Locomotor tests in open-field and rotarod activities are parameters experimentally used to assess stressor-induced behavioral disorders
McElhatton PR, Sullivan FM, Volans GN
In contrast, Ginkgo biloba constituents have moderate oral bioavailability and undergo hepatic metabolism, with plasma half-life that may require several days of dosing to reach stable pharmacodynamic effects
Rapamycin for refractory discoid lupus erythematosus
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