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Coherus said the observationcommunicated in an FDA Form 483is readily addressable and the company continues to anticipate potential approval for toripalimab by year end 2023. Coherus and its partner Junshi Biosciences received a CRL for toripalimab in this indication requesting a quality process change in May 2022

Overall, current evidence supports the notion that G6PD downregulation may favor the onset and evolution of atheroma in subjects at risk of CVD

As an antioxidant, glutathione helps fight free radicals, unstable molecules that can damage cells and have been linked to inflammation and a host of age-related diseases from high blood pressure and Alzheimers to heart disease and cancer

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