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In addition to mimicking the hormone responsible for satiety, Zepbound also imitates GIP (Glucose-Dependent Insulinotropic Polypeptide), which influences how the body breaks down sugar and fat, further reducing appetite

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doi:10.1007/s40279-016-0543-8

However, as treatment progresses and GLP-1 levels rise during refeeding, they may remain elevated, potentially contributing to delayed gastric emptying and lower postprandial glucose levelsfactors that can complicate the refeeding process as the body adjusts to normal intake (126)

Trials have also looked at their potential to help patients with a wide range of conditions ranging from heart disease to opioid overdose and alcohol intoxication.