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3.2.3 FUNDC1 mediated mitophagy The FUN14 domain-containing protein 1 (FUNDC1) is widely present on the mitochondrial outer membrane and acts as a regulator of mitochondrial autophagy in response to hypoxia, inducing Parkin-independent mitophagy (Liu et al., 2012)

Glutathione supports energy levels Glutathione plays a protective role in the cells, ensuring the mitochondria - which is the powerhouse of the cell, working to produce energy - isnt damaged by oxidative stress

van Nuland, R

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Upon binding to IGF-1R, the peptide initiates multiple intracellular signaling cascades, including the phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway, which regulates protein synthesis and cell growth, and the mitogen-activated protein kinase (MAPK) pathway, which controls cell proliferation and survival