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B GM & L ocation BGM, 1

disrupted iron metabolism results in local iron overload and augmented Fenton reactions

Experimental Materials All extracellular flux analysis consumables were purchased from Agilent (North Billerica, MA, USA)

Notably, the bacteriums carcinogenic potential was formally recognized by the International Agency for Research on Cancer (IARC) in 1994, classifying it as a Group 1 carcinogen (Schistosomes, liver flukes and Helicobacter pylori, 1994)

1105 However, the specific protective mechanisms of these drugs still require further investigation, including their impact on mitochondrial complexes, modulation of the calcium ion balance, and stabilization of mtDNA