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5.1 Mechanism of intranasal delivery Since William Frey II proposed intranasal administration in 1991 (Frey, 1991), this technique has emerged as a novel, non-invasive delivery system, bypassing the BBB and the systemic first-pass effect, allowing rapid onset of action

Within approved clinical trials, all reconstitution and preparation is carried out by trained healthcare professionals under strictly controlled, protocolised conditions this cannot be replicated in a home setting

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Caution is recommended in patients with a psychotic disorder (e.g., schizophrenia due to insufficient data

A: DopeRx BPC-157 is intended for parenteral (injection) use and must be administered by a healthcare professional as per prescribed guidelines