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doi: 10.1016/s0092-8674(00)81865-6 106 YeoGSHChaoDHMSiegertAMKoerperichZMEricsonMDSimondsSEet al

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GLP-1RAs excel at inducing short-term weight loss by imposing a powerful external satiety signal, whereas postbiotics may contribute to stabilizing the endogenous signaling environment that governs appetite regulation and metabolic adaptation ( Adipose tissue plasticity and thermogenic capacity: BAT, browning, and the physiological ceiling in humans The discovery of metabolically active BAT in adult humans raised expectations that obesity therapies might meaningfully increase energy expenditure through thermogenesis (30)