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Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration

doi: 10.3389/fphar.2026.1755175 Received 26 November 2025 Revised 21 January 2026 Accepted 20 February 2026 Published 09 March 2026 Volume 17 - 2026 Edited by Roland Bcker, Charit University Medicine Berlin, Germany Reviewed by Mark Lloyd Dapar, Central Mindanao University, Philippines Kishor Jain, Sinhgad Institutes, India Updates Copyright 2026 Kayesh, Kohara and Tsukiyama-Kohara

For the last several decades the link between cardiovascular diseases and antioxidants has been investigated using cell cultures, animal models, and clinical trials (Dludla et al