As a prescription medication, it functions as a GLP-1 receptor agonist, which means it mimics the incretin hormones that the body naturally produces to stimulate insulin release after eating
The anti-inflammatory activity of the products under investigation was determined by measuring the levels of an anti-inflammatory cytokine (IL-10) secreted by RAW 264.7 cells after stimulation with lipopolysaccharide (LPS)
(Extended reading: After Tirzepatide's approval for the treatment of obesity, how long will it be before Eli Lilly's small molecule GLP-1R agonist becomes available?) Volenrelaxin (LY3540378) is a long-acting synthetic relaxin analogue that acts as an agonist for the relaxin family peptide receptor 1 (RXFP1), developed by Eli Lilly for the treatment of chronic heart failure
Wegovy has the same active ingredient as Ozempic, semaglutide
However, real-world experiences vary by individual, dose level, and titration speed