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Meta-analyses indicate that GLP-1RAs generally reduce HOMA-IR and improve fasting blood glucose and 2 h OGTT levels in the PCOS population (78)

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While Raibick said her initial use of semaglutide helped her gain the confidence she needed to hit the gym and adjust her diet, she was worried about titrating, or weaning off of the drug, and subsequently gaining back the weight shes lost

Of note, gluconeogenesis was blocked by allulose in rats receiving a Western diet (Figure 2C)

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