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After week 48, with the start of the open-label treatment extension period, group 1 (placebo) and group 2 (bimagrumab 10 mg kg 1 ) switched to receive bimagrumab 30 mg kg 1 every 12 weeks without the loading dose

TMAO might serve as a precise biomarker for conditions like mortality, cardiovascular diseases, diabetes, cancer, and kidney function [7]