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The SOUL trial (NCT06659718) will investigate the effect of semaglutide on cardiovascular outcomes in patients with T2DM who have preexisting cardiovascular disease and/or CKD

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Diabetologia 65(12):19251966 [DOI] [PMC free article] [PubMed] [Google Scholar] 6.Berra C, Manfrini R, Mirani M, Bucciarelli L, Zakaria AS, Piccini S et al (2023) AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus

Visceral versus subcutaneous fat While the trial did not break down visceral and subcutaneous fat reduction separately using imaging for all participants, the liver fat data serves as a strong proxy

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