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Consistency and a healthy lifestyle amplify the benefits

Healthcare professionals should provide individualised advice based on patient-specific factors including: Body weight and composition (larger individuals generally require more fluid) Concurrent medications (particularly diuretics or other agents affecting fluid balance) Comorbidities (such as chronic kidney disease or heart failure, which may require fluid restriction) Physical activity levels (increased activity necessitates additional fluid replacement) Climate and environmental factors (hot weather increases insensible losses) Patients should be encouraged to monitor their urine colour as a simple indicator of hydration status, aiming for pale straw-coloured urine throughout the day

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With the above reasons, we set new inclusion/exclusion criteria and additional database search for the study so that we could investigate whether allulose is effective in healthy humans or not

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