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Protocol modifications: Start lower doses (BPC-157 200mcg vs 500mcg, GHK-Cu 1mg vs 3mg) with slower titration, simplify regimens (once daily vs multiple doses), prioritize evidence-based options (Cerebrolysin for glaucoma over speculative peptides), involve family members in administration and monitoring, focus on most impactful intervention if resources limited

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Then, 30 years later, they tested the participants cognitive abilities multiple times over a span of 2 years (a total of 5 tests)