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The increased level of those PUFAs could be due on one hand, to an increased biosynthesis linked to a high expression of the fatty acid desaturases 1 and 2 (FADS1/2) as shown in TNBC [36]

The 9 mg and 12 mg doses tested in TRIUMPH-4 are expected to form the therapeutic range, with 2 mg as the starting dose

Tranexamic acid is a synthetic derivative of the amino acid lysine

A score of three or more should prompt referral, especially when features such as inflammation, oozing or bleeding, and change in sensation are present