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When combined with nanoencapsulation, such digital twins could be used to test how different carrier designs, doses and dosing schedules affect simulated post-prandial responses, nutrient status or inflammatory markers before any intervention is implemented in vivo (255)

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Although some circadian changes have been reported for bioactive components, the current evidence is still limited for drawing definitive conclusions [17]

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Chemical synthesis using solid-phase peptide synthesis (SPPS) is suitable for shorter peptides and allows for precise control over peptide structure