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3 Importantly, hair loss is not listed as a common side effect in the original semaglutide prescribing information, but pharmacovigilance data and post-marketing reports have made the association increasingly clear

26 Experiments in pancreatic islets reveal that -arrestin limits the insulin response to GLP-1, but not GIP or tirzepatide, suggesting that the biased agonism and imbalance of tirzepatide toward the GIP receptor and its unique GLP-1 receptor signaling properties might be at the basis of its potent action

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Results 4.1

Demographics of GLP-1 Users Women comprise roughly 6065% of GLP-1 users, driven by higher obesity prevalence and greater engagement with preventive health strategies