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This hormone is a key player in managing both blood sugar and appetite

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This affordability threshold acknowledges that even if a drug passes the cost-effectiveness test, a very large patient group at threshold price could strain the NHS budget

Although the FLOW trial and the secondary analysis of the SELECT trial have demonstrated important kidney benefits of semaglutide, the kidney-protective effects of other GLP-1 receptor agonists are less well known, as there have not been prospective trials with kidney outcomes, and it is unclear whether the benefits of these medications are a class effect or are medication specific