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A rough way to think about it: If 4 in 10,000 people have an outcome, and another group has 9 in 10,000, that is more than double, yes

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However, the study authors highlight that further research is necessary, as its unclear whether the increased dietary restraint that GLP-1s may contribute to is helpful for self-control or may instead lead to imbalanced forms of restricted eating, such as skipping meals

Tirzepatide Dosing Tiers: From Initiation Through Maintenance Tirzepatide dosing typically follows a step-up protocol to allow the body to adapt and minimize gastrointestinal side effects