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Consequently, RNAi is used in functional genomics (systematic analysis of loss-of-function phenotypes induced by RNAi triggers) and developing therapies for the treatment of viral infection, dominant disorders, neurological disorders, and many types of cancers (in vivo inactivation of gene products linked to human disease progression and pathology)

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We observed a significant decrease in the number and area of tumor nodules in the Cpt1a -knockout mice ( Cpt1a -/- ) compared to the control mice ( Cpt1a +/+ ), also a prolonged survival time (Fig

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