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The highest monotherapy dose studied is 4.5 mg per week (Lancet 2021 Phase 2)

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Micrographs are representative images of three independent experiments

Administer the filler into the submucosal or intradermal layers of the gingival tissue at a depth of 2-4 mm below the mucosal surface

These effects often improve with dose adjustments and time, but they should be monitored by your clinician