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KLOTHO functions as a co-receptor in several crucial intracellular signaling pathways, and its reduced expression in the body may result in cardiovascular diseases, induction of inflammation, or promotion of aging [134]
Literature describes subcutaneous administration in research models
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In addition, B12 deficiency-associated fatigue is often accompanied by other symptoms such as numbness and tingling, cognitive impairment (memory and concentration problems), mood swings (depression), skin changes (pale skin), shortness of breath, or fast heart rate
In fact, the dropout rate due to side effects was low about 10%
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