glutathione conjugation paracetamol Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors paracetamol | MedChemExpress (MCE) Life

Acknowledgements This study was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MIST) under grant number 2021R1G1A1091690

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Mitochondrial DNA (mtDNA), which encodes 13 essential subunits of the electron transport chain (ETC), is particularly susceptible to oxidative stress, resulting in replication errors, point mutations, and large-scale deletions (Robichaux et al., 2023)