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Isotonic formulations or compositions are provided by the addition of a tonicity agent

The branded formulation Ozempic recently also became FDA approved to reduce the risks of major cardiovascular outcomes in adults with type 2 diabetes mellitus with known heart disease, and to reduce the risk of kidney damage and cardiovascular related deaths in adults with type 2 diabetes mellitus and chronic kidney disease (CKD).It works by enhancing insulin release, reducing glucagon production, and slowing stomach emptying, which can reduce appetite, increase feelings of fullness, and encourage weight loss

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Cole RN, Hart GW

Thandapani, P