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Keystone, E

SAMe ultimately plays a role in numerous methylation reactions catalyzed by methyltransferase enzymes including the synthesis of hormones, neurotransmitters, nucleic acids, proteins, and phospholipids (Mischoulon)

Interestingly, the absence of eosinophils was associated with increased expression of both Th1 (e.g., Ifng ) and Th2 (e.g., Il4 , Il10 , Il13 ) cytokines in the affected tissue (Fig