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The researchers used the Mayo Clinic Platform, a healthcare database covering 8 million patients, to find about 580 people with IBD who had taken GLP-1 drugs

Immunohistochemical analysis of biopsy and postmortem samples revealed increased expression of UPR markers, including CHOP and BiP, in oligodendrocytes, astrocytes, T cells, and macrophages/microglia within MS lesions