We interpret this result as being due to pyocyanin-mediated decline in GRed activity that manifests as insufficient enzymatic activity for the conversion of exogenously added GSSG to GSH
generic challenger who finds the narrowed EPO claim is not infringed by their proposed product has evidence that the brand itself acknowledged the claims limitations, an argument that can influence claim construction even in U.S
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DOI: Published online: April 19, 2021 1 Toronto General Hospital Research Institute, University Health Network, ON, Canada 2 Division of Nephrology, Department of Medicine, University of Toronto, ON, Canada 3 Banting and Best Diabetes Centre, University of Toronto, ON, Canada 4 Applied Health Research Centre, Li Ka Shing Knowledge Institute of St Michaels Hospital, ON, Canada 5 Department of Physiology, University of Toronto, Toronto, ON, Canada 6 Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada Corresponding author: David Z.I
10.1176/ajp.148.9.1159 Am