Medication (dose) Nausea Vomiting Diarrhea Constipation Dyspepsia (indigestion) Wegovy (semaglutide 2.4 mg) 44% 24% 30% 24% 9% Ozempic (semaglutide 1.0 mg) 20% 9% 9% 3% 2.7% Rybelsus (semaglutide 14 mg) 20% 8% 10% 5% Less than 1% Saxenda (liraglutide 3 mg) 39% 16% 21% 19% 10% Victoza (liraglutide 1.8 mg) 20% 9% 12% 5% 7% What will this feel like across a typical day and week
Barnett AH, Charbonnel B, Donovan M, et al
Future research will be needed to assess whether the new CBT for BED, which combines GLP-1RAs for a subset of patients, is more effective than existing psychological treatments for BED associated with obesity
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Less common, but milder, side effects of semaglutide injections Some side effects of semaglutide injections for weight loss seen in clinical trials are less common but still mild and include: Indigestion (dyspepsia) Dizziness Abdominal distention (bloating) Belching (eructation) Low blood sugar (hypoglycemia) in people with type 2 diabetes Flatulence Gastroenteritis Gastroesophageal reflux disease (GERD) Gastritis Gastroenteritis viral Hair loss An abnormal touch sensation (dysesthesia) These side effects were reported fewer than 9% of trial participants