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Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience: Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions

Specific problems addressed include defining pharmacodynamic endpoints, performing clinical trials in this population and assessing developmental changes in both pharmacokinetics and pharmacodynamics

The purpose of titration is to find the lowest effective dose that produces results without intolerable side effects

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How do I adjust the vitamin B12 injection dosage for special conditions, such as renal impairment or malabsorption disorders