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Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-Activity relationship studies

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Often referred to as the bodys "master antioxidant," glutathione is essential for detoxification, immune function, and cellular repair

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In summary, artesunate inhibits the activation of M1 macrophages and the RIPK1/RIPK3/MLKL signaling cascade by down-regulating Mincle expression, consequently reducing both the inflammatory response and necroptosis, thereby ameliorating renal injury in AKI