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The authors observed Gb3 accumulation in diseased iPSC-CMs, but not in isogenic control cells

Staining was performed with o -phenylenediamine (Sigma-Aldrich)

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However, when dopaminergic neurons (the cells responsible for this conversion) are stressed in PD, their ability to perform this conversion becomes impaired

105 Obstructive sleep apnea, a sleep disorder characterized by repeated episodes of partial or complete airway obstruction during sleep and closely linked to cardiovascular and metabolic diseases, has also been associated with rosacea