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backup contraception is advised for 4 weeks after initiation and after each dose increase

Keeping your fluid levels up is key to helping your body recover: Drink water frequently throughout the day Consider oral rehydration sachets to restore electrolyte balance (always check with a clinician first if you have any kidney problems) Choose gentle, easy to digest foods until symptoms settle Avoid alcohol, very fatty foods, and spicy meals while your stomach is sensitive Know the signs of dehydration Losing fluids can sometimes lead to dehydration, so keep an eye out for early symptoms like: dry mouth dark urine fatigue dizziness headaches muscle cramps When to seek urgent help Severe dehydration needs medical attention

Maintains bowel length and function while relieving symptoms caused by strictures

The -subunit participates in ATP hydrolysis through conformational changes of the enzyme, switching the enzyme between E1 and E2 conformations that switch the enzyme affinity to Na + and K + , respectively