Collectively, our findings suggest that Gsta4 and physiological levels of 4-HNE regulate differentiation of OLs and that this has clinical relevance in in vivo models of inflammation- or toxin-induced demyelination
The peptide was originally identified in human plasma and has been widely studied in laboratory environments investigating collagen production pathways, tissue remodeling mechanisms, and extracellular matrix regulation
Ellouk-Achard S, Levresse V, Martin C, Pham-Huy C, Dutertre-Catella H, Thevenin M et al
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