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In pivotal clinical trials for Wegovy, nausea was reported by approximately 44% of patients, while Ozempic trials reported nausea in 15-20% of participants

It also generates foam that makes it impossible to verify whether the powder has fully dissolved

Medicines that already slow gastric emptying, such as anticholinergics and some antiemetics, can compound gastrointestinal effects

Additionally, the updated results (July 2023) of the tirzepatide SURMOUNT-1 trial recorded an average reduction in body weight of 22.5%

Plans should also ensure Wegovy is added to a transition exclusion list to ensure only Part D eligible medically accepted indications are afforded a transition fill