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doi: 10.1055/s-2007-981457 86 FortunatoRSFerreiraACHechtFDupuyCCarvalhoDP

doi: 10.1038/s41598-024-75965-2

Briefly, the brain homogenate was diluted 1:20 (v:v) with ice-cold Lockes buffer (154 mM NaCcl, 5.6 mM KCl, 3.6 mM NaHCO3, 2.0 mM CaCl2, 10 mM D-glucose and 5 mM HEPES, pH 7.4) to obtain a concentration of 10 mg tissue/ml

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There are some mechanisms by which tesofensine may contribute to increased fat burning such as increased metabolism, appetite suppression, and modulation of neurotransmitters